This is a great article from two of my favorite preachers. They are very different and yet this article shows how they are similar in what I am passionate about (unchurched).
Here are some suggestions on how to engage the lost people listening to you preach.
1. Acknowledge and welcome the non-believers in attendance.
2. Assume the non-believers in attendance need help in approaching the Bible.
3. Challenge non-believers to engage the Bible by acknowledging the oddity of Christian belief and practice.
4. Use cultural commonalities to point out worldview inconsistencies.